The scholarly study of 1 1,157 patients between 18 and 70 years who were seeking major treatment at an urban general medication clinic serving a low-income population. Between December 2001 and January 2003 The analysis was conducted.A diagnosis of bipolar disorder was dependant on different questionnaires and surveys and reviewing data about past mental health remedies and records. The experts discovered that the prevalence of positive screening outcomes for life time bipolar disorder was 9.8 % and do not differ by age significantly, sex, or race/ethnicity. Eighty-one sufferers who screened positive for bipolar disorder sought specialized help because of their symptoms, but only 9 reported finding a medical diagnosis of bipolar disorder.Dr. Mangelsdorf says the study may also explain why females are better safeguarded than men from coronary disease until they reach the menopause. At that time the findings triggered a panic and a large number of females acquiring hormone replacements to alleviate menopause symptoms stopped using the therapy. Mangelsdorf says by the time the ladies started taking estrogen again, the damage due to 27HC binding to the estrogen receptors in the heart may already have occurred as soon as this happens it cannot be regained. The experts also discovered that when 27HC binds to estrogen receptors in other tissues, such as for example reproductive tissues, no effect is had because of it on their reproduction-related functions.