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CU scientist talks about reward circuits in the brain Why does one individual become anorexic and another obese? A study recently published by a University of Colorado School of Medicine researcher implies that reward circuits in the mind are sensitized in anorexic ladies and desensitized in obese females. The findings also claim that eating behavior relates to brain dopamine pathways involved with addictions. Guido Frank, MD, assistant professor director of the Developmental Mind Research System at the CU School of Medication and his colleagues used useful magnetic resonance imaging to examine brain activity in 63 women who had been either anorexic or obese.