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CAR T-cell therapy enters into Stage I clinical trial Cancer tumor fighting chimeric antigen receptor T cells, developed in the Sentman laboratory of Dartmouth's Norris Cotton Cancer Center, are taking the next phase into a Stage I clinical trial beginning early in 2015. Charles Sentman, PhD, initial published this novel use CAR T cells in Blood in 2005 and in Cancer Research in 2006. They demonstrated that their CAR therapies may have broad applicability for most different cancers, and further discovered that CAR therapy not merely eliminated tumors from pets, but also prevented tumor recurrence india tadalafil .

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